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NAD+ treatments for Chronic Conditions

Millions of Australians are affected by some chronic illness. These conditions are typically long lasting with persistent effects. Their social and economic consequences can impact on peoples’ quality of life. For many people, it is difficult to do the things they enjoy and often leads to depression and a feeling of hopelessness.

NAD+ therapy has been shown to be capable of dramatically reducing symptoms of these illnesses by boosting the body’s natural cell repair.

There has been remarkable anecdotal evidence of patients reporting incredible results from NAD+ treatment both here and in the US.

AgelessNAD has introduced intravenous NAD+ treatment supported by oral NAD+ supplements to help Australians suffering from chronic conditions regain their energy and strength. We aim to be at the forefront of learning more about the benefits of NAD+ in treating other diseases. As researchers and experts discover additional use for NAD+, we will make sure to incorporate those therapies in our clinic.


CFS is a complex, multisystem condition with a multitude of symptom, mainly characterized by long-lasting, disabling fatigue (both physical and mental) that cannot be explained by any underlying medical condition. The cause of CFS remains unclear, although there are many contributors including hormonal imbalance, autoimmune dysfunction, toxic chemical/heavy metal exposure, and viral/bacterial/parasitic infections. One known theory, however, traces the pathology of CFS to defects in energy provision at the cellular level known as ‘mitochondrial dysfunction’.

Mitochondrial Dysfunction

Each cell in our bodies has tiny components called ‘mitochondria’, whose job is to convert oxygen and food that we take in into usable energy in the form of ATP (adenosine triphosphate). In addition to providing energy, they play a major role in combating oxidative stress, a condition that causes breakdown and damage of cells and DNA.

Mitochondria impact the metabolism of all cells, therefore playing a huge role in health. When mitochondria fail, there is reduction in energy supply which results in the bodily functions slowing down. This is a characteristic of aging, and essentially, all chronic diseases including neurodegenerative diseases, cardiovascular diseases, autoimmune diseases, mental illnesses, diabetes and metabolic syndrome, gastrointestinal disorders, and fatiguing illnesses, such as CFS.

Chronic Fatigue and Mitochondrial Dysfunction

The notion that mitochondrial dysfunction can cause excess fatigue is based on the observation that fatigue is a common symptom of mitochondrial disease. The relation between these two conditions has been mainly studied in patients with CFS.

A study reveals that 70% of Chronic Fatigue Syndrome patients have abnormally functioning mitochondria. Biomedical tests utilized to examine markers of mitochondrial function showed that patients tested have measurable mitochondrial dysfunction which correlates with the severity of the illness.

Nicotinamide Adenine Dinucleotide (NAD) and Chronic Fatigue

The process of generating energy from food requires a co-enzyme, nicotinamide adenine dinucleotide (NAD). It plays a critical role in mitochondrial energy production and cellular metabolism homeostasis.

Emerging data suggests that deficiencies in NAD and CoQ10 have been identified in CFS patients. A recent clinical trial done concluded that supplementation with NAD and CoQ10 can effectively reduce the fatigue and aid in mitochondrial function restoration in long-term CFS patients, and perhaps other chronic fatiguing illnesses.